Behavioural Effects of Aerial Parts of Alysicarpus glumaceus Vahl DC in Murine Models

Abstract Background Alysicarpus glumaceus has been reported to be used in managing patients with neuropsychiatric disorders. This work aimed determine the behavioural effects of aerial parts murine models. Method The drug extract was evaluated using elevated zero maze (EZM), stair case test (SCT) and open field (OFT) while beam walking for motor coordination deficit stimulant activity mice at doses 500, 1000 1500 mg/kg diazepam (0.05 mg/kg) as standard normal saline (NS) control. Results All reduced stretch attend posture head dips well number rearing without significant decrease stairs climbed EZM SCT respectively when compared NS. In OFT, increased square crossing but it insignificant ( p >0.05). significantly <0.01) decreased rearing; 500 <0.001) rearing. At all used, there no difference time reach goal box foot slips, however, given produced a <0.05) increase spent on beam. Conclusion findings revealed that possesses central nervous system depressant actions.